Persistent STAG2 mutation despite multimodal therapy in recurrent pediatric glioblastoma
نویسندگان
چکیده
منابع مشابه
The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent STAG2 Mutation
The Ewing sarcoma family of tumors (EFT) is a group of highly malignant small round blue cell tumors occurring in children and young adults. We report here the largest genomic survey to date of 101 EFT (65 tumors and 36 cell lines). Using a combination of whole genome sequencing and targeted sequencing approaches, we discover that EFT has a very low mutational burden (0.15 mutations/Mb) but fre...
متن کاملCorrection: The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent STAG2 Mutation
There are several errors in the published manuscript. 1. There are 4 instances where NFATc2 is misspelled as NCATc2; in the 6 line of the abstract, in the first paragraph of the subsection ‘‘Tumors lacking a EWSR1-ETS fusion have distinct molecular characteristics from the remaining majority Ewing sarcoma family tumors’’ in the Results section and twice in the second paragraph of the Discussion...
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ژورنال
عنوان ژورنال: npj Genomic Medicine
سال: 2020
ISSN: 2056-7944
DOI: 10.1038/s41525-020-0130-7